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Case 02

Case 02

Oct 09, 2026

This case demonstrates how OCT imaging, together with OCT-FFR, ICA, and Lumens Splicing, enabled comprehensive assessment of a long coronary lesion, guided tailored lesion preparation, and confirmed anatomical and physiological improvement following PCI.

Pre-PCI

The patient presented with progressive CCS class III angina. Coronary CTA revealed a high calcium burden (Agatston score >400), with a diffuse diseased segment extending approximately 65–70 mm.

Two pre-intervention OCT pullbacks were combined using Lumens Splicing to enable comprehensive visualization of the entire lesion.

OCT revealed predominantly diffuse fibrous plaque with focal, non-circumferential calcification.

Baseline OCT measurements:
Minimum lumen area (MLA):
1.38 mm²
OCT-FFR:
0.66

ICA further characterized the most severe calcified segment:

  • Maximum calcium arc: ~156°
  • Maximum calcium thickness: ~1.1 mm
  • Calcium length: ~4.2 mm
  • 555 calcium score: 1

Despite the high CTA calcium score, OCT findings supported a targeted lesion-preparation strategy rather than aggressive calcium modification.

After Lesion Preparation

High-pressure non-compliant balloon dilatation combined with a cutting balloon was performed to modify the predominantly fibrous lesion.

Repeat OCT demonstrated effective plaque modification with multiple controlled plaque incisions.

MLA increased:
1.38 → 2.23 mm²
  • Key OCT finding: multiple controlled plaque incisions
  • Clinical implication: improved lesion compliance without major thrombotic complications

These findings supported proceeding with stent implantation.

After Stenting

Two stents, measuring 45 mm and 35 mm, were implanted to cover the long diseased segment.

Two consecutive post-PCI OCT pullbacks were acquired and combined using Lumens Splicing, generating a continuous dataset of approximately 95 mm for comprehensive assessment of the entire stented segment.

Final OCT

Final OCT confirmed satisfactory stent expansion and complete strut apposition, with calcium fracture observed at previously calcified sites.

Minimum stent area (MSA)
~4.8 mm²
Stent apposition
100%
OCT-FFR
0.66 → 0.95

The final assessment demonstrated marked physiological improvement and satisfactory anatomical results following OCT-guided PCI.

▶ Full case video and detailed OCT workflow on LinkedIn:
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